Thyroxine Chemical Structure
Levothyroxine is a synthetic levoisomer of thyroxine t4 similar to the endogenous hormone produced by the thyroid gland.
Thyroxine chemical structure. T3 enters the cell and binds to nuclear thyroid hormone receptors and the hormone receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration thermogenesis cellular growth and differentiation and metabolism of proteins. It is a tautomer of a thyroxine zwitterion. O 4 hydroxy 35 dii odophenyl 35 diiod o l tyrosine. Thyroxine is commonly referred to in the blood reports as t4.
Thyroxinealso known as t4 or l 3535 tetraiodothyronine triiodothyroninet3 or l 353 triiodothyronine as shown in the following diagram the thyroid hormones are basically two tyrosines linked together with the critical addition of iodine at three or four positions on the aromatic rings. Levothyroxine is a synthetic form of thyroxine t 4 an endogenous hormone secreted by the thyroid gland which is converted to its active metabolite l triiodothyronine t 3. Thyroxine t 4 contains four iodine atoms while triiodothyronine t 3 otherwise identical to t 4 has one less iodine atom per molecule. The amino acid is bound to the thyroglobulin protein.
C1c cc c c1ioc2cc c c c2ioiic catath c oon. Thyroxines principal function is to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. So it is also known as 3 5 3 5 tetraiodothyronine. Thyroxine is de iodinated to form triiodothyronine t3 in the peripheral tissues.
T 4 and t 3 bind to thyroid receptor proteins in the cell nucleus and cause metabolic effects through the control of dna transcription and protein synthesis. Thyroxine also called 3535 tetraiodothyronine or t4 one of the two major hormones secreted by the thyroid gland the other is triiodothyronine. It is the inactive form and most of it is converted to an active form called triiodothyronine by organs such as the liver and kidneys. Tyrosine o 4 hydr oxy 35 diiodopheny l 35 diiodo acdindex name 300 30 1 200 102 7 einecs 2228514 beilstein 2 amino 3 4 4 hyd roxy 35 diiodophen oxy 35 diiodophen ylpropanoic acid.
Chemical structure of thyroxine. Thyroid hormones play vital roles in regulating the bodys metabolic rate heart and. Inchi1sc15h11i4no4 c16 8 4 7 5 9 1713 82124 14 10 181 6 2 11 14193 12 20 15 2223h1 24 51 221h320h2 h222 3t12 m0s1. It has a role as a mitogen.
Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. It is an iodothyronine a 2 halophenol an iodophenol a tyrosine derivative and a non proteinogenic alpha amino acid. 2 amino 3 4 4 hyd roxy 35 diiodophen oxy 35 diiodophen ylpropanoic acid. Thyroxine is an iodothyronine compound having iodo substituents at the 3 3 5 and 5 positions.
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Do you need anything, like a medicine maybe?